VIROCIDAL ACTIVITY OF EGYPTIAN SCORPION VENOMS AGAINST HEPATITIS C VIRUS

Xojimurodov Davronjon Ikramaliyevich

Angren University, Angren City, Tashkent Region Teacher of the Faculty of Medicine Angren University, Angren City,

Mirzayev Furqat Farhod o'g'li

Tashkent Region Teacher of the Faculty of Medicine

Keywords: Keywords: Hepatitis C virus, HCV, Antiviral activity, Scorpion venom, Scorpio maurus palmatus, Egypt, HCV-Hepatitis C virus, SVR-Sustained virological response, AMPs-Antimicrobial peptides, CC50-50% cytotoxic concentration,IC50 -50% inhibitory concentration.


Abstract

Hepatitis C virus (HCV) is a major global health problem, causing chronic hepatitis, liver cirrhosis and hepatocellular carcinoma. Development of well-tolerated regimens with high cure rates and fewer side effects is still much needed. Recently, natural antimicrobial peptides (AMPs) are attracting more attention as biological compounds and can be a good template to develop therapeutic agents, including antiviral agents against a variety of viruses. Various AMPs have been characterized from the venom of different venomous animals including scorpions.


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