INSTRUMENTAL AND TREATMENT TACTICS WHEN STROKE AND ACUTE CORONARY SYNDROME OCCUR SIMULTANEOUSLY IN ONE PATIENT
Keywords:
Stroke, acute coronary syndrome, simultaneous occurrence, instrumental diagnostics, treatment tactics, cardiovascular diseases, imaging techniques, pharmacological therapy, interventional treatment, hemodynamic monitoring, patient management, multidisciplinary approach.Abstract
Stroke and acute coronary syndrome (ACS) are critical cardiovascular conditions that require urgent and precise management. The simultaneous occurrence of both conditions in a single patient presents a unique clinical challenge due to overlapping symptoms and complex pathophysiology. This article reviews the instrumental diagnostic approaches and treatment strategies for managing patients with concurrent stroke and ACS. Emphasis is placed on timely diagnosis using imaging and laboratory tests, careful evaluation of hemodynamic status, and the integration of pharmacological and interventional therapies to optimize patient outcomes. The article also discusses potential complications and the need for multidisciplinary collaboration in the management of such high-risk patients. Understanding and implementing effective diagnostic and therapeutic tactics is crucial for improving prognosis and reducing morbidity and mortality in this patient group.
Downloads
References
1. Adams, H. P., del Zoppo, G., Alberts, M. J., et al. (2007). Guidelines for the early management of adults with ischemic stroke. Stroke, 38(5), 1655-1711.
2. Ibragimov, S. A., & Tursunov, D. S. (2019). Diagnostic approaches in acute stroke patients. Central Asian Journal of Neurology, 4(2), 45-52. (In Uzbek).
3. Antman, E. M., Anbe, D. T., Armstrong, P. W., et al. (2004). ACC/AHA guidelines for management of ST-elevation myocardial infarction. Circulation, 110(9), e82-e292.
4. Karimov, B., & Yuldashev, M. (2017). Management of acute coronary syndrome in Uzbekistan. Uzbek Medical Journal, 3(1), 23-30. (In Uzbek).
5. Hacke, W., Kaste, M., Bluhmki, E., et al. (2008). Thrombolysis with alteplase 3 to 4.5 hours after acute ischemic stroke. NEJM, 359(13), 1317-1329.
6. Nasirov, R., & Rashidov, A. (2020). Combined stroke and myocardial infarction: Clinical challenges. Journal of Cardiovascular Medicine of Uzbekistan, 6(1), 12-19. (In Uzbek).
7. Jneid, H., Anderson, J. L., Wright, R. S., et al. (2012). 2012 ACCF/AHA update for unstable angina/non-STEMI management. JACC, 60(7), 645-681.
8. Rakhimov, M. (2018). Stroke and ACS: Contemporary approaches to treatment. Tashkent Medical Bulletin, 7(4), 58-65. (In Uzbek)
9. Kernan, W. N., Ovbiagele, B., Black, H. R., et al. (2014). Guidelines for the prevention of stroke. Stroke, 45(7), 2160-2236.
10. Smith, S. C., Feldman, T. E., Hirshfeld, J. W., et al. (2006). ACC/AHA/SCAI 2005 guideline update for PCI. JACC, 47(1), 216-235.
11. Yuldashev, A., & Tadjiev, F. (2019). Role of multidisciplinary teams in management of complex cardiovascular patients. Uzbek Clinical Cardiology Journal, 2(3), 33-39. (In Uzbek)
12. Zipes, D. P., Libby, P., Bonow, R. O., et al. (2018). Braunwald's Heart Disease: A Textbook of Cardiovascular Medicine. 11th Edition. Elsevier.



















