Multidisciplinary Journal of Science and Technology

GLOMERULONEPHRITIS IN CHILDREN

Arzibekova Umida Abdukadirovna

Senior teacher of the Department of Pediatrics and Neonatology of the Faculty, ASMI

Keywords: glomerulonephritis, children, nephritic syndrome, post-streptococcal GN, kidney inflammation, pediatric nephrology, proteinuria.

Abstract

Glomerulonephritis (GN) in children represents a heterogeneous group of renal diseases characterized by inflammation of the glomeruli, the filtering units of the kidney. It can manifest acutely or chronically, with symptoms ranging from microscopic hematuria to nephrotic-nephritic syndrome and progressive renal failure. This article provides a comprehensive overview of the etiology, pathophysiology, clinical manifestations, diagnostic approaches, and therapeutic strategies related to pediatric glomerulonephritis. Special attention is paid to post-infectious glomerulonephritis, IgA nephropathy, lupus nephritis, and the emerging role of immunomodulatory therapy. Emphasis is placed on early detection, multidisciplinary care, and long-term monitoring to prevent chronic kidney disease.

References

1. Eddy, A. A., & Symons, J. M. (2013). Nephrotic syndrome in childhood. The Lancet, 362(9384), 629–639.

2. Tarshish, P., et al. (2014). Long-term outcome of children with postinfectious glomerulonephritis. Pediatrics, 113(2), 356–362.

3. Noone, D. G., et al. (2018). Glomerulonephritis in children. Pediatric Clinics of North America, 65(1), 179–197.

4. Bagga, A., & Hari, P. (2012). Nephrotic syndrome and glomerular disease in children. Indian Journal of Pediatrics, 79(7), 934–940.