PATHOLOGICAL ANATOMY AND CAUSES OF ANTENATAL DEATH: INSIGHTS FROM PLACENTAL HISTOLOGY

Z. X. Alauatdiinova

Tashkent Medical Academy, Tashkent, Uzbekistan

K. N. Babaev

Tashkent Medical Academy, Tashkent, Uzbekistan

Keywords: Antennatal fetal death, stillbirth, perinatal mortality, placental insufficiency


Abstract

Significant advancements in obstetric and neonatal care have led to a gradual decrease in perinatal mortality rates globally and within the Russian Federation. While this improvement is largely due to reductions in early neonatal mortality, the rising stillbirth rate has become a pressing concern, representing an increasing proportion of perinatal mortality. Despite the development of modern prenatal diagnostic techniques, biochemical marker evaluations for identifying pregnancy complications, and targeted referrals of high-risk patients for specialized ultrasound examinations, the challenge of antenatal fetal death remains inadequately addressed. In developed nations, as much as 60% of stillbirths are currently classified as unexplained, in contrast to 4.7% in the Russian Federation. This situation underscores a critical need for enhanced understanding of the mechanisms underlying antenatal fetal death, which is essential for developing effective preventive strategies and improving maternal-fetal outcomes.


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