Multidisciplinary Journal of Science and Technology

Study of the Quality of Life Characteristics of Patients with Ischemic Heart Disease, Chronic Kidney Disease, and Type 2 Diabetes Mellitus

G.B.Shoymurodova

Tashkent Medical Academy

D.K.Nuritdinova

Tashkent Medical Academy

S.K Nuritdinova

Tashkent Medical Academy

Keywords: ischemic heart disease, chronic kidney disease, type 2 diabetes mellitus

---

Abstract

This compilation provides a comprehensive overview of the quality of life characteristics of patients dealing with ischemic heart disease (IHD), chronic kidney disease (CKD), and type 2 diabetes mellitus (T2DM). It highlights the interconnected nature of these chronic conditions, emphasizing that patients with CKD and T2DM experience high residual cardiorenal morbidity and mortality, as well as an increased risk of cardiovascular events. Key findings from recent studies indicate that chronic conditions like CKD significantly deteriorate patients' quality of life (QoL) due to complications such as cardiovascular morbidity, fatigue, and anemia.

Cardiac rehabilitation (CR) emerges as a critical component for secondary prevention in IHD patients, demonstrating effectiveness in reducing recurrent cardiovascular events and improving mortality rates while enhancing patients’ ability to return to work. With international guidelines recommending comprehensive CR programs, the necessity for assessment and improvement of patient engagement in CR is highlighted, especially in the context of Poland, where referral and participation rates remain low. Moreover, medication adherence is identified as a crucial factor influencing health outcomes, with significant variability among CKD patients, further reinforcing the need for patient-centered care approaches.

The annotation also delves into the prevalence of T2DM, indicating its status as a leading global public health issue, particularly in Turkey and Iran, where significant segments of the population are affected. It stresses the importance of self-management practices and education to enhance patients' capabilities in managing their conditions, thereby improving their overall health and QoL.

Further discussing psychosocial aspects, the text notes the prevalence of depression and anxiety in CKD patients, emphasizing the necessity for timely interventions that can mitigate these mental health concerns and enhance treatment outcomes. Overall, this collection of information underscores the need for integrated care strategies that encompass physical, psychological, and educational support to improve the quality of life for individuals suffering from IHD, CKD, and T2DM

---

References

1. Agarwal R., Filippatos G., Pitt B., Anker S.D., Rossing P., Joseph A., Kolkhof P., Nowack C., Gebel M., Ruilope L.M., Bakris G.L. Cardiovascular and kidney outcomes with finerenone in patients with type 2 diabetes and chronic kidney disease: the FIDELITY pooled analysis // Diabetes Care. – 2022. – Vol. 45, № 4. – P. 476 [1].

2. Sinnadurai S., Sowa P., Jankowski P., Gąsior Z., Kosior D.A., Haberka M., Czarnecka D., Pająk A., Setny M., Jamiołkowski J., Łapińska M., Kamiński K.A. Effects of cardiac rehabilitation on risk factor management and quality of life in patients with ischemic heart disease: a multicenter cross-sectional study // Journal of Cardiopulmonary Rehabilitation and Prevention. – May 31, 2021. – P. 617-618 [2].

3. Impact of training based on Orem's theory on self-care agency and quality of life in patients with coronary artery disease // Journal of Nursing Research. – December 2020. – Vol. 1, № 1. – P. 6 [3].

4. Willems S., Tilz R.R., Steven D., Kääb S., Wegscheider K., Gellér L., Meyer C., Heeger C.-H. Preventive or Deferred Ablation of Ventricular Tachycardia in Patients With Ischemic Cardiomyopathy and Implantable Defibrillator (BERLIN VT) A Multicenter Randomized Trial // European Heart Journal. – March 31, 2020. – P. 1058 [4].

5. McGregor G., Powell R., Kimani P., Underwood M. Does contemporary exercise-based cardiac rehabilitation improve quality of life for people with coronary artery disease? A systematic review and meta-analysis // Heart. – November 29, 2019. – P. 2 [5].

6. Tesfaye W.H., McKercher C., Peterson G.M., Jose M., Zaidi S.T.R., Wimmer B.C. Medication adherence, burden and health-related quality of life in adults with predialysis chronic kidney disease: A prospective cohort study // Nephrology. – 2020. – P. 2-3 [6].

7. Gadia P., Awasthi A., Jain S., Koolwal G.D. Depression and anxiety in patients of chronic kidney disease undergoing haemodialysis: A study from western Rajasthan // Indian Journal of Nephrology. – 2020. – P. 4283 [7].

8. van Haalen H., Jackson J., Spinowitz B., Milligan G., Moon R. Impact of chronic kidney disease and anemia on health-related quality of life and work productivity: analysis of multinational real-world data // Clinical Kidney Journal. – 2020. – P. 2-3 [8].

9. Magadi W., Lightfoot C.J., Memory K.E., Santhakumaran S., van der Veer S.N., Thomas N., Gair R., Smith A.C. Patient activation and its association with symptom burden and quality of life across the spectrum of chronic kidney disease stages in England // BMC Nephrology. – 2022. – P. 2-3 [9].

10. Abedini M.R., Bijari B., Miri Z., Shakhs Emampour F., Abbasi A. The quality of life of the patients with type 2 diabetes using EQ-5D-5L in Birjand // Journal of Diabetes & Metabolic Disorders. – 2020. – P. 2-6 [10].

11. Fidan Ö., Takmak Ş., Zeyrek A.Ş., Kartal A. Patients With Type 2 Diabetes Mellitus: Obstacles in Coping // Journal of Diabetes Research. – August 4, 2020. – P. 4-8 [11].

12. De Groot J., Wu D., Flynn D., Robertson D., Grant G., Sun J. Efficacy of telemedicine on glycaemic control in patients with type 2 diabetes: A meta-analysis // Diabetes Research and Clinical Practice. – February 15, 2021. – P. 172 [12].