DEVELOPMENT OF NEPHROPATHY IN THE CONTEXT OF OVERWEIGHT AND OBESITY: A LITERATURE REVIEW

Abstract

Overweight and obesity are considered important risk factors not only for metabolic syndrome, arterial hypertension and cardiovascular diseases, but also for the development of chronic kidney disease. In obesity, insulin resistance, dyslipidemia, chronic low-grade inflammation, endothelial dysfunction and glomerular hyperfiltration are formed. These changes contribute to microalbuminuria, a decrease in renal filtration function and the gradual development of nephropathy.