BAKTERIYALARDA ANTIBIOTIKLARGA REZISTENTLIK RIVOJLANISH MEXANIZMLARI VA UNING KLINIK AHAMIYATI

Authors

  • Jumanova Sarvinoz Toshkent Davlat Tibbiyot Unversiteti talabasi Toshkent, Uzbekistan
  • Baxridinova Mohina Toshkent Davlat Tibbiyot Universiteti talabasi Toshkent, Uzbekistan
  • Valijon Masharipov Toshkent Davlat Tibbiyot Universiteti Mikrobiologiya, immunologiya va virusologiya kafedrasi katta o'qituvchisi. Tibbiyot fanlar nomzodi Toshkent, Uzbekistan

Keywords:

antibiotics, bacteria, resistance, microorganisms, beta-lactamase, infection, antimicrobial therapy.

Abstract

Antibiotics are essential therapeutic agents in the treatment of bacterial infections. In recent years, the increasing resistance of microorganisms to antibiotics has become one of the most pressing challenges in global healthcare. This article analyzes the molecular-biological mechanisms of antibiotic resistance development in bacteria, the factors leading to the formation of resistant strains, and their significance in clinical practice. Furthermore, the importance of the rational use of antibiotics and the oversight of antimicrobial therapy are discussed.

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References

1. World Health Organization (WHO). Global antimicrobial resistance and use surveillance system (GLASS) report 2022. Geneva: WHO, 2022.

2. Azizov I.S., et al. Antibiotiklarga rezistentlikning molekulyar asoslari. Toshkent: Tibbiyot nashriyoti, 2020.

3. Bush K., Bradford P.A. β-Lactamases and β-Lactamase Inhibitors in Clinical Practice. Expert Review of Anti-infective Therapy, 2016; 14(9): 803-818.

4. Saidov A.B., Jumanazarov Q. Klinik mikrobiologiya va antimikrob terapiya asoslari. Toshkent: Ibn Sino nomidagi nashriyot, 2021.

5. Davies J., Davies D. Origins and Evolution of Antibiotic Resistance. Microbiology and Molecular Biology Reviews, 2010; 74(3): 417-433.

6. O‘zbekiston Respublikasi Sog‘liqni saqlash vazirligi. Antimikrob preparatlardan oqilona foydalanish bo‘yicha milliy qo‘llanma. Toshkent, 2023.

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Published

2026-03-25

How to Cite

BAKTERIYALARDA ANTIBIOTIKLARGA REZISTENTLIK RIVOJLANISH MEXANIZMLARI VA UNING KLINIK AHAMIYATI. (2026). International Conference on Multidisciplinary Science, 4(3), 40-42. https://mjstjournal.com/index.php/icms/article/view/7087