EFFECTS OF KIDNEY DYSFUNCTION ON DISEASE COURSE IN PATIENTS WITH CHRONIC HEART FAILURE.

Norboyev A.A.

Republican Specialized Scientific and Practical Medical Center of Cardiology, Tashkent, Uzbekistan.

Boqiyeva D. R

Tashkent medical academy, Tashkent, Uzbekistan

Xodjanova Sh. I

Tashkent medical academy, Tashkent, Uzbekistan.

##semicolon## Chronic heart failure, cardiorenal syndrome, chronic kidney disease (CKD)


सार

The functions of the heart and kidneys are closely interrelated. Their interaction can be defined as a complex biological relationships between distant organs, which are mediated through cellular, canlecular, nervous, endocrine and paracrineed factors. Under physiological conditions this connection.Helps maintain homeostasis and optimal functioning of the human body. Deterioration the function of one of these organs is caused by a vicious range of events leading to multi-organ failure

accuracy. Although it is well known about the dysfunction renal function in patients with heart disease, it remains unclear whether renal dysfunction is passive response to cardiac failure activity. In clinical practice throughout the for more than 13 years, the term “cardiorenal syndrome" (CDS), i.e. coexistence cardiac and renal nature in the same patient.


##submission.citations##

ВЛИЯНИЕ ПОЧЕЧНОЙ ДИСФУНКЦИИ НА СЕРДЕЧНО-СОСУДИСТУЮ СИСТЕМУ. ВОЗМОЖНОСТИ РАННЕЙ ДИАГНОСТИКИ ПОЧЕЧНОЙ ДИСФУНКЦИИ . Б.Ж. Иманов1 , И.Т. Муркамилов*2,3 , И.С. Сабиров 3 , А.Ш. Сарыбаев

Krane V., Wanner C. Statins, inflammation and kidney disease. Nat Rev

Nephrol.2011;7(7):385397.doi:10.1038/nrneph.2011.62https://dio:10.3389/fphys.2019.01108

Lai S., Ciccariello M., Dimko M.et al. Cardio-Renal Syndrome Type 4:

The Correlation Between Cardiorenal Ultrasound Parameters.

Kidney Blood Press Res. 2016;41(5):654-662. DOI:https://doi.

org/10.1159/000447934.https://dio:10.1016/j.ijcard.2018.04.001

,, Assosiation between renal function and cardiovascular structure and function in heart failure with preserved ejection fraction”. Gori M, Senni M, Gupta D., Chartyan D, et al (2014) Eur , Heart j. 35, 3442-3451 https://dio:10.1093/eurheartj/ehu254

Domenici A., Luciani R., & Principe F. Pulmonary hypertension in

dialysis patients. Perit Dial Int. 2010; 30(2): 251-252. DOI:10.3747/

pdi.2009.00082.

,, Chronic kidney disease induces left ventricular overexpression of the prohypertopic micro RNA -212 “ Sarkozy M, Gaspar R. Zvara A.Siska A. Kovari B. Szucs G.et al (2019) Sci . Rep. 9:1302

http://dio10.1038/s41598-018-37690-5

,,Cardiovascular implications of proteinuria: an indicator of chronic kidney

disease.’’ Agrawal, V., Marinescu, V., Agarwal, M., and McCullough, P. A. (2009) Nat. Rev. Cardiol. 6, 301–311. http://doi:10.1038/nrcardio.2009.11

,,Left ventricular hypertrophy in new hemodialysis patients without symptomatic

cardiac disease.” Foley, R. N., Curtis, B. M., Randell, E. W., and Parfrey, P. S. (2010) Clin. J. Am. Soc. Nephrol. 5, 805–813. http://doi:10.2215/CJN.07761109

Testani JM, Chen J, McCauley BD, Kimmel SE, Shannon RP

(2010) Potential effects of aggressive decongestion during the

treatment of decompensated heart failure on renal function and

survival. Circulation 122:265–272

Verbrugge FH, Dupont M, Steels P, Grieten L, Swennen Q et al

(2014) The kidney in congestive heart failure: ‘are natriuresis,

sodium, and diuretics really the good, the bad and the ugly?’. Eur

J Heart Fail 16:133–142

Fudim M, Loungani R, Doerfler SM, Coles A, Greene SJ et al

(2018) Worsening renal function during decongestion among

patients hospitalized for heart failure: findings from the Evaluation Study of Congestive Heart Failure and Pulmonary Artery

Catheterization Effectiveness (ESCAPE) trial. Am Heart J

:163–173

Милованов Ю.С., Фомин В.В., Милованова Л.Ю. Трудностикоррекции гиперфосфатемии у больных хронической почечной

недостаточностью. Место не содержащих кальций фосфорсвя-

зывающих препаратов. Тер. Архив. 2016; 88(6): 95-100.