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2024-01-07
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ACHILLEA MILLEFOLIUM L., POLYGONUM AVICULARE L., GLYCYRRHIZA GLABRA L., POLYGONUM HYDROPIPER L. , MATRICARIA CHAMOMILLA L. STUDY OF THE EFFECT OF NEW COLLECTION ON ANEMIA, OBTAINED ON THE BASIS OF PLANTS
Kh. O. Darmanov
Tashkent State Pharmaceutical Institute
Keywords: phytopheron, hemolytic anemia, drug, coamide, rat, peripheral blood, phenylhydrazine, hemoglobin, erythrocyte, leukocyte.
Abstract
The effect of the phytoferon drug on the course of hemolytic anemia at doses of 5 and 10 mg/kg was studied in laboratory rats. Based on the results obtained, on the 15th day of the experiment, Phytopheron at a dose of 5 mg/kg increased the amount of hemoglobin in the peripheral blood by 0.9 g % compared to the state of anemia, and the amount of erythrocytes by 0.3 mln, respectively. It was found that increased by, while at a dose of 10 mg/kg, the amount of hemoglobin and erythrocytes increased more intensively by 1.3 g % and by 0.45 mln, respectively. On the 30th day of the experiment, however, its stimulating effect on hematopoiesis was further increased, noting that the amount of hemoglobin increased by 2.3 g % and 3.4 g%, respectively, according to the indicators of the state of anemia. The amount of erythrocytes in the peripheral blood was also observed to increase to 0.85 mln and 1 mln respectively on the 15th and 30th days of the experiment compared to the indicators of the state of anemia. Under the influence of phytopheron, negative changes in the morphology of erythrocytes and leukocytes were significantly reduced.
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